From Nizza di Sicilia
you can easily reach Taormina, Etna, Aeolian Islands, Messina, Catania, Caltagirone, Siracusa, Noto, Piazza Armerina, Palermo.
Arriving at the airport of Catania, where there are major international companies to rent a car, arrived in Nizza di Sicilia in 50' along the highway Catania-Messina until exit of Roccalumera.
Coming by car directly from the continent, should take the highway from Messina to Catania, which will take  15' to exit of Roccalumera.